Beneficiality of combined levetiracetam, clonazepam for myoclonus in MERRF requires further confirmation
نویسندگان
چکیده
منابع مشابه
Suppression of Myoclonus in Corticobasal Degeneration by Levetiracetam
Myoclonus in corticobasal degeneration (CBD) has often been associated with severe and difficult to treat disabilities. Levetiracetam is a new antiepileptic agent with antimyoclonic effects. Herein, we present a 72-year-old woman with clinically probable CBD and with spontaneous rhythmic myoclonus in the right foot, which was markedly ameliorated through treatment with levetiracetam. The effect...
متن کاملAntiepileptic treatment and blood lactate level alteration in patients with myoclonic epilepsy with ragged-red fi bers (MERRF) syndrome in a Chinese family
Background: Myoclonic epilepsy with ragged-red fi bers (MERRF) is a type of mitochondrial encephalomyopathy, clinical experience with the antiepileptic treatment for myoclonus in MERRF is still limited. Myoclonus appears to be intractable, and some antiepileptic drugs may change the blood lactate level. Objective: In this study, we report on two patients, a girl and her mother, both with MERRF ...
متن کاملStimulus-induced myoclonus treated effectively with clonazepam in genetically confirmed Coffin–Lowry syndrome☆
PURPOSE Coffin-Lowry syndrome (CLS) is a rare X-linked semidominant syndromic genetic disorder that is characterized by typical facial and radiologic findings, psychomotor and growth retardation, and various skeletal anomalies. A distinctive paroxysmal disorder called stimulus-bound myoclonus is clinically heterogeneous and is generally characterized by a sudden loss of muscle tone that is rega...
متن کاملEffective high-dose clonazepam treatment in two patients with opsoclonus and myoclonus: GABAergic hypothesis.
both patients have been described in detail elsewhere [5] . Briefly, two consecutive young adults aged 34 and 29 years exhibited repeated vomiting, vertigo, truncal ataxia, opsoclonus and generalized myoclonus. Both deteriorated to the peak of clinical disability 1 month later when they lost the ability to walk and were confined to bed. In both patients, the cellular and humoral CSF alterations...
متن کاملstudy of cohesive devices in the textbook of english for the students of apsychology by rastegarpour
this study investigates the cohesive devices used in the textbook of english for the students of psychology. the research questions and hypotheses in the present study are based on what frequency and distribution of grammatical and lexical cohesive devices are. then, to answer the questions all grammatical and lexical cohesive devices in reading comprehension passages from 6 units of 21units th...
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ژورنال
عنوان ژورنال: Chinese Medical Journal
سال: 2019
ISSN: 0366-6999
DOI: 10.1097/cm9.0000000000000042